12/2/2023 0 Comments Ab negative blood![]() ![]() Plaque rupture was identified by the presence of disrupted fibrous cap. Thin-cap fibroatheroma (TCFA) was defined as the thinnest fibrous cap thickness ≤65 μm in lipid-rich plaque on a cross-sectional image. The fibrous cap thickness (FCT) of lipid-rich plaque was measured at its thinnest part 3 times, and the average value was then calculated. For lipid plaque, the lipid arc was measured at every 1 mm interval throughout the entire length of lipid length. ![]() Plaques were classified into 2 categories: (1) fibrous (homogeneous high signal region) or (2) lipid plaque (low signal region with diffuse border). If any portion of the image was outside the screen, if a side branch occupied >45° of the cross-section, or if the image was of poor quality due to residual blood, sew-up artifact, or reverberation, then it was excluded from the analysis. Cross-sectional images were screened for quality assessment. Cross-sectional OCT images were analyzed at 1 mm intervals along the pullbacks. If there was discordance in interpretations between the observers, a consensus reading was obtained by corresponding author. The OCT images of target lesions were analyzed by two independent investigators. The methods of intracoronary OCT imaging have been described previously. The time-domain OCT system (M2/M3 Cardiology Imaging System LightLab Imaging, Inc., Westford, Massachusetts) or the frequency-domain OCT system (C7-XR OCT Intravascular Imaging System St. In this study, we aimed to analyze OCT images of coronary artery plaque in CAD patients and compare the morphological characteristics between different blood type groups. Optical coherence tomography (OCT) has been widely used for coronary plaque characterization. We hypothesized that the high level of cholesterol in non-O blood increased the risk of CAD and MI by playing an essential role in the progress of atherosclerotic plaque. An association of ABO blood group with total cholesterol and low-density lipoprotein cholesterol has long been recognized and non-O blood group have higher cholesterol absorption rates and higher levels of total cholesterol and low-density lipoprotein cholesterol. However, the underlying mechanisms for the relationship between ABO blood groups and CAD were unclear. Moreover, clinical data on the association of ABO blood groups with severity of CAD have shown that ABO blood groups were significantly related to severity of CAD, non-O blood group was found to be the independent predictors of high SYNTAX score, and O blood group was shown as a protective factor of high Gensini score. Recent metastudy also confirmed that non-O blood group appears to be an independent risk factor for CAD and myocardial infarction, and non-O blood group was associated with a statistically significant 14% increase in CAD incidence relative to O blood group. Previous studies have shown that ABO blood groups, particularly the non-O blood groups, are associated with risk factor of coronary artery disease (CAD). The ABO histoblood group is one of the major human blood antigen systems, classified by the presence of A and B antigens on the surface of red blood cells. Moreover, the non-O type blood group have more serious coronary artery stenosis than O type blood group. The plaques of O type blood group were exhibited more stably compared with non-O type blood group. The fibrous cap thickness was significantly thicker in O type compared with non-O type (0.075 ± 0.033 mm versus 0.061 ± 0.024, p 0.05). Subjects were divided into different groups according to different blood types. We retrospectively identified the target lesions in 392 acute coronary syndrome patients who underwent optical coherence tomography examination before stenting. We aimed to evaluate the relationship between ABO blood groups and the coronary plaque characteristic. The ABO blood types related to morphological characteristics of atherosclerosis plaque are not clear. ![]()
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